Description

Omega-3 is a type of polyunsaturated fatty acid derived mainly from fish oil. These important nutrients are commonly used in nutritional therapy for depression, high cholesterol and to reduce the risk of heart attack(1).

Studies indicate omega-3 fatty acids can lower cholesterol (2) (6) and may reduce recurrence in patients with a history of stroke (5).

Omega 3s have also been shown to be beneficial in the area of oncology because they play essential roles in cell signaling and in the cell structure and fluidity of membranes(15). They participate in the resolution of inflammation and have anti-inflammatory and antinociceptive effects(4).

Higher omega-3 intake and improved survival among stage III colon cancer patients with wild-type KRAS and deficient MMR (13)
Supplementation with Omega-3 was also associated with reduced occurrence of renal cell carcinoma in women (3) and may lower the risk of breast cancer (7); improve overall survival (14) from cancer.

Preliminary findings suggest that fish oil supplementation increases efficacy of chemotherapy, improves survival (8), and helps maintain weight and muscle mass (9) in patients with non-small cell lung cancer (NSCLC); and improves quality of life scores in gastrointestinal cancer patients  (12).

Additional studies found an EPA-enriched oral supplement improved tolerability of chemotherapy in advanced colorectal cancer patients (10); and when combined with chemotherapy, fish oil supplements may delay tumor progression in those with colorectal cancer (11).

1. https://www.mskcc.org/cancer-care/integrative-medicine/herbs/omega-3
2. Kabir M, Skurnik G, Naour N, et al.Treatment for 2 mo with n 3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: a randomized controlled study. Am J Clin Nutr 2007 Dec;86(6):1670-9.
3. Wolk A, Larsson SC, Johansson J, Ekman P.Long-term fatty fish consumption and renal cell carcinoma incidence in women. JAMA 2006;296(11):1371-1376.
4. Weiss G, Meyer F, Matthies B, Pross M, Koenig W, Lippert H.Immunomodulation by perioperative administration of n-3 fatty acids. Br J Nutr 2002;87 Suppl 1:S89-S94.
5. Tanaka K, Ishikawa Y, Yokoyama M, et al.Reduction in the recurrence of stroke by eicosapentaenoic acid for hypercholesterolemic patients: subanalysis of the JELIS trial. 2008 Jul;39(7):2052-8.
6. Gunnarsdottir I, Tomasson H, Kiely M, et al.Inclusion of fish or fish oil in weight-loss diets for young adults: effects on blood lipids. Int J Obes. 2008;32(7):1105-12.
7. Brasky TM, Lampe JW, Potter JD, Patterson RE, White E.Specialty Supplements and Breast Cancer Risk in the VITamins And Lifestyle (VITAL) Cohort. Cancer Epidemiol Biomarkers Prev. 2010;19(7); 1696-708.
8. Murphy RA, Mourtzakis M, Chu QS, et al.Supplementation with fish oil increases first-line chemotherapy efficacy in patients with advanced nonsmall cell lung cancer. 2011;117(16):3774-80.
9. Murphy RA, Mourtzakis M, Chu QS, et al.Nutritional intervention with fish oil provides a benefit over standard of care for weight and skeletal muscle mass in patients with nonsmall cell lung cancer receiving chemotherapy.  2011 Apr 15;117(8):1775-82.
10. Trabal J, Leyes P, Forga M, Maurel J.Potential usefulness of an EPA-enriched nutritional supplement on chemotherapy tolerability in cancer patients without overt malnutrition.Nutr Hosp. 2010 Sep-Oct;25(5):736-40.
11. Camargo Cde Q, Mocellin MC, Pastore Silva Jde A, Fabre ME, Nunes EA, Trindade EB.Fish oilsupplementation during chemotherapy increases posterior time to tumor progression in colorectal cancer. Nutr Cancer. 2016;68(1):70-6.
12. Sim E, Kim JM, Lee SM, et al. The Effect of Omega-3 Enriched Oral Nutrition Supplement on Nutritional Indices and Quality of Life in Gastrointestinal Cancer Patients: A Randomized Clinical Trial.Asian Pac J Cancer Prev.2022 Feb 1;23(2):485-494.
13. Song M, Ou FS, Zemla TJ, et al.Marine omega-3 fatty acid intake and survival of stage III colon cancer according to tumor molecular markers in NCCTG Phase III trial N0147 (Alliance).Int J Cancer. 2019 Jul 15;145(2):380-389.
14. Darwito D, Dharmana E, Riwanto I, et al.Effects of Omega-3 Supplementation on Ki-67 and VEGF Expression Levels and Clinical Outcomes of Locally Advanced Breast Cancer Patients Treated with Neoadjuvant CAF Chemotherapy: A Randomized Controlled Trial Report. Asian Pac J Cancer Prev.2019 Mar 26;20(3):911-916.
15. Raquel D. S. Freitas, Maria M. Campos. Protective Effects of Omega-3 Fatty Acids in Cancer-Related Complications. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566772/

Each bottle contains: 60 softgels

Serving size: 1 softgel

Servings per container: 60

Each serving contains:

Calories: 10

Total Fat: 1g

Fish Oil: 1100mg

EPA (Eicosapentaenoic Acid): 400mg

DHA (Docosahexaenoic Acid): 300mg

Other ingredients: Gelatin, glycerin, purified water

Suggested use: Take 1 softgel daily or as directed by your healthcare provider.

Keep out of reach of children.

Store in a cool dark place

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease